Model Information

ALL-SIL

Overview

Name(s) ALL-SIL (SIL-ALL)

Tissue Haematopoietic and Lymphoid

Cancer Type T-Lymphoblastic Leukemia

Tissue Status Tumour

Sample Site Peripheral Blood

Cancer Type Details Childhood T Acute Lymphoblastic Leukemia   (NCIT C7953)

GDSC Growth Estimate 1.42 +/- 0.30 (19 replicates)

Derivation

Model Type Cell Line

Growth Properties Suspension

Model treatment

Year Generated

Model Genomics

MSI Status MSS

Ploidy (SNP6) 2.048

Ploidy (WES) 2.149

Mutations per Mb 29.13

Summary

Gender Male

Ethnicity Unknown

Age at sampling 17

History

Smoker Status Unknown

Diagnosis & Treatment

Tumour Stage No Data

Prior treatment Unknown

Clinical Profiling

Loading cancer drivers
Mutations & Copy Number Alterations
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RNASeq
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Proteomics
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Gene Fusions
Loading Gene Fusions
Dataset Availability

  • Whole Exome Sequencing
    Processed SIDM00994_Sanger_wes_indel_vaf.pindel.annot_drv.vcf.gz (28.42 kB) - Source: Sanger
    Raw Whole Exome Sequencing (BAM/CRAM) - Source: Sanger
    Processed SIDM00994_Sanger_wes_snp_vaf.caveman_c.annot_drv.vcf.gz (178.26 kB) - Source: Sanger
    Processed SIDM00994_Broad_wes_indel_vaf.pindel.annot_drv.vcf.gz (29.04 kB) - Source: Broad
    Processed SIDM00994_Broad_wes_snp_vaf.caveman_c.annot_drv.vcf.gz (145.17 kB) - Source: Broad
  • Microarray Gene Expression
    Raw Microarray Gene Expression (CEL) - Source: Sanger
  • RNASeq
    Processed SIDM00994_rnaseq.csv.zip (554.44 kB) - Source: Broad
  • Copy Number Variation
    Processed SIDM00994_WES_pureCN_CNV_segments.csv.zip (31.62 kB) - Source: mixed
    Processed SIDM00994_Sanger.PureCN_GATK.WES.panel.cnv.pdf (89.67 kB) - Source: Sanger
    Raw Copy Number Variation - Source: Sanger
    Processed SIDM00994_WES_pureCN_CNV_genes.csv.zip (1.53 MB) - Source: mixed
  • DNA Methylation
    Raw DNA Methylation (IDAT) - Source: Sanger
  • Fusion data
    Processed SIDM00994_fusions.csv.zip (400 B) - Source: Sanger
  • Proteomics
    Processed SIDM00994_proteomics.csv.zip (98.71 kB) - Source: Sanger
    • Identifiers
    Suppliers
    Note:  * denotes a commercial supplier.

    Cell Model Passports

    • UI Version: 1.14.0
    • API Version: 1.16.0
    • Data Version: 2.13.0

    Websites

    Contact

    depmap@sanger.ac.uk

    Wellcome Sanger Institute
    Wellcome Genome Campus
    Hinxton, Cambridgeshire
    CB10 1SA, UK

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